Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | FASN | P49327 | 13/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RBP4 | P02753 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731334 | 0.88 | FASN (0.63) | LMNAFASNALDH1A1HPGDHSD11B1 | |
| SCHEMBL14209216 | 0.88 | ALDH1A1 (0.52) | LMNAFASNALDH1A1HPGDTP53 | |
| SCHEMBL4733674 | 0.88 | ALDH1A1 (0.52) | LMNAFASNALDH1A1HPGDTP53 | |
| SCHEMBL4175647 | 0.87 | PARP10 (0.56) | LMNAFASNALDH1A1HPGDTP53 | |
| SCHEMBL4191753 | 0.86 | PARP10 (0.58) | LMNAFASNALDH1A1HPGDTP53 | |
| SCHEMBL4197739 | 0.86 | FASN (0.61) | FASNALDH1A1HPGDTP53MAPT | |
| SCHEMBL16799271 | 0.86 | HPGD (0.50) | LMNAFASNALDH1A1HPGDTP53 | |
| SCHEMBL4735211 | 0.85 | CA12 (0.58) | LMNAFASNALDH1A1HPGDTP53 | |
| SCHEMBL4195205 | 0.84 | ALDH1A1 (0.48) | LMNAFASNALDH1A1HPGDTP53 | |
| SCHEMBL4183575 | 0.83 | CA12 (0.53) | LMNAFASNALDH1A1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |