Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.51 |
| ▸ | CCR8 | P51685 | 1/20 | 0.51 |
| ▸ | SFRP1 | Q8N474 | 6/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | WNT3 | P56703 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732371 | 0.92 | SFRP1 (0.50) | CCR8SFRP1BRD4USP30STS | |
| SCHEMBL17394215 | 0.89 | STS (0.53) | CCR8SFRP1BRD4USP30STS | |
| SCHEMBL4734475 | 0.88 | MCHR1 (0.54) | MCHR1ADRA2ANPY5RSFRP1KDM4E | |
| SCHEMBL4735664 | 0.86 | SFRP1 (0.58) | CCR8SFRP1BRD4USP30STS | |
| SCHEMBL3947055 | 0.84 | MCHR1 (0.54) | MCHR1ADRA2ANPY5R | |
| SCHEMBL3947061 | 0.84 | MCHR1 (0.54) | MCHR1ADRA2ANPY5R | |
| SCHEMBL3006664 | 0.83 | MCHR1 (0.66) | MCHR1ADRA2ANPY5R | |
| SCHEMBL16013308 | 0.83 | STS (0.61) | CCR8SFRP1BRD4USP30STS | |
| SCHEMBL16124960 | 0.82 | CCR8 (0.52) | CCR8SFRP1BRD4USP30STS | |
| SCHEMBL3027665 | 0.81 | MCHR1 (0.61) | MCHR1ADRA2ANPY5RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061016-A1 | N-SUBSTITUTED PIPERIDINYL 4 -ARYLSULFONAMIDES AS MODULATORS OF THE SECRETED FRIZZLED RELATED PROTEIN- 1 | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |