Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13900227 | 0.85 | SMN1; SMN2 (0.54) | ELANELMNAMAPTHTTALDH1A1 | |
| SCHEMBL25688979 | 0.85 | LMNA (0.53) | ELANEACHEBCHELMNAMAPT | |
| SCHEMBL25407106 | 0.85 | ELANE (0.51) | ELANEACHEBCHELMNAMAPT | |
| SCHEMBL3813706 | 0.83 | MAPT (0.51) | ELANEACHEBCHELMNAMAPT | |
| SCHEMBL27670799 | 0.83 | ALDH1A1 (0.48) | ELANEACHEBCHELMNAMAPT | |
| SCHEMBL29185989 | 0.83 | ELANE (0.51) | ELANEMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL27495399 | 0.83 | ELANE (0.40) | ELANEACHEBCHELMNAMAPT | |
| SCHEMBL27514766 | 0.83 | KMT2A (0.51) | ELANEACHEBCHELMNAMAPT | |
| SCHEMBL1893211 | 0.82 | ALDH1A1 (0.51) | ELANELMNAMAPTHTTALDH1A1 | |
| SCHEMBL27623698 | 0.82 | ACHE (0.38) | ELANEACHEBCHELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343775-B1 | PIPERAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-06-04 | — | — | EP | claimed |