Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.56 |
| ▸ | WNT3A | P56704 | 4/20 | 0.56 |
| ▸ | FLT3 | P36888 | 2/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RBP4 | P02753 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8232893 | 0.84 | KDM4E (0.61) | KDM4EYTHDC1STAT3HIF1ACTNNB1 | |
| SCHEMBL30451174 | 0.81 | KDM4E (0.62) | KDM4EYTHDC1STAT3HIF1ACTNNB1 | |
| SCHEMBL7668372 | 0.81 | KDM4E (0.66) | KDM4EYTHDC1STAT3HIF1ACTNNB1 | |
| SCHEMBL31148407 | 0.81 | KDM4E (0.66) | KDM4EYTHDC1STAT3HIF1ACTNNB1 | |
| Trifluoroacetic Acid SCHEMBL15546473 | 0.80 | FLT3 (0.54) | KDM4EYTHDC1STAT3HIF1ACTNNB1 | |
| SCHEMBL4066785 | 0.80 | KDM4E (0.60) | KDM4EYTHDC1STAT3HIF1ACTNNB1 | |
| SCHEMBL29444537 | 0.79 | FLT3 (0.65) | KDM4EYTHDC1STAT3HIF1ACTNNB1 | |
| SCHEMBL5353834 | 0.79 | FLT3 (0.65) | KDM4EYTHDC1STAT3HIF1ACTNNB1 | |
| SCHEMBL42245 | 0.79 | FLT3 (0.65) | KDM4EYTHDC1STAT3HIF1ACTNNB1 | |
| SCHEMBL217086 | 0.78 | KDM4E (0.67) | KDM4EYTHDC1STAT3HIF1ACTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109134376-B | Synthetic method of 3-trifluoroacetyl indazole derivative | 华南理工大学 | 2021-09-21 | — | — | CN | claimed |
| CN-109134376-B | Synthetic method of 3-trifluoroacetyl indazole derivative | 华南理工大学 | 2021-09-21 | — | — | CN | disclosed |
| CN-109134376-B | Synthetic method of 3-trifluoroacetyl indazole derivative | 华南理工大学 | 2021-09-21 | — | — | CN | disclosed |
| CN-109134376-B | Synthetic method of 3-trifluoroacetyl indazole derivative | 华南理工大学 | 2021-09-21 | — | — | CN | disclosed |
| WO-2008074757-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2008-06-26 | — | — | WO | disclosed |