Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 15/20 | 0.64 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.44 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733976 | 0.90 | FASN (0.53) | FASNPROKR1 | |
| SCHEMBL4737584 | 0.88 | FASN (0.74) | FASN | |
| SCHEMBL4731958 | 0.85 | FASN (0.72) | FASN | |
| SCHEMBL4736239 | 0.84 | FASN (0.74) | FASN | |
| SCHEMBL4737156 | 0.84 | FASN (0.72) | FASNTP53MAPT | |
| SCHEMBL4731407 | 0.82 | FASN (0.71) | FASN | |
| SCHEMBL4784807 | 0.81 | FASN (0.70) | FASN | |
| SCHEMBL4735742 | 0.81 | FASN (0.64) | FASNUBE2MDCUN1D1 | |
| SCHEMBL16802696 | 0.81 | FASN (0.69) | FASN | |
| SCHEMBL4733280 | 0.81 | FASN (0.69) | FASNPROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |