Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9584249 | 0.85 | MEN1 (0.66) | CA1CA2MEN1KMT2ACYP1A2 | |
| SCHEMBL31242942 | 0.83 | KDM4E (0.63) | PARP1KCNK3KCNK9MEN1KMT2A | |
| SCHEMBL316626 | 0.83 | KDM4E (0.63) | PARP1KCNK3KCNK9MEN1KMT2A | |
| SCHEMBL13331944 | 0.83 | PARP1 (0.58) | CA1CA2PARP1P2RX7KCNK3 | |
| SCHEMBL11350516 | 0.82 | P2RX7 (0.55) | CA1CA2PARP1P2RX7KCNK3 | |
| SCHEMBL4154673 | 0.82 | ALDH1A1 (0.56) | CA1CA2P2RX7MEN1KMT2A | |
| SCHEMBL9491028 | 0.82 | NAMPT (0.70) | MEN1KMT2ANAMPT | |
| SCHEMBL3815582 | 0.82 | P2RX7 (0.55) | CA1CA2PARP1P2RX7KCNK3 | |
| SCHEMBL9489991 | 0.82 | NAMPT (0.70) | MEN1KMT2ANAMPT | |
| Hydrochloric Acid SCHEMBL15137104 | 0.81 | KDM4E (0.61) | PARP1KCNK3KCNK9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582696-B1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2014-10-22 | — | — | EP | disclosed |
| WO-2011157748-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2011-12-22 | — | — | WO | disclosed |