Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | PARP1 | P09874 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.56 |
| ▸ | FEN1 | P39748 | 1/20 | 0.56 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | AOC2 | O75106 | 1/20 | 0.54 |
| ▸ | FLT1 | P17948 | 1/20 | 0.54 |
| ▸ | FLT4 | P35916 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31242942 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1PARP1L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL15137104 | 0.98 | KDM4E (0.61) | KDM4EALDH1A1PARP1L3MBTL1LMNA | |
| Cyanide SCHEMBL29178066 | 0.94 | KDM4E (0.58) | KDM4EALDH1A1PARP1L3MBTL1LMNA | |
| SCHEMBL5353587 | 0.88 | KCNK3 (0.72) | KCNK3KCNK9MEN1KMT2ARAB9A | |
| SCHEMBL10441487 | 0.86 | S1PR1 (0.51) | KDM4EALDH1A1PARP1L3MBTL1LMNA | |
| SCHEMBL77384 | 0.85 | ALDH1A1 (0.76) | KDM4EALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL3717147 | 0.85 | KMT2A (0.60) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7174674 | 0.83 | MEN1 (0.70) | ALDH1A1PARP1L3MBTL1KCNK3KCNK9 | |
| SCHEMBL11064749 | 0.83 | PKM (0.67) | KDM4EALDH1A1PARP1L3MBTL1KCNK3 | |
| SCHEMBL47363 | 0.83 | CA1 (0.57) | ALDH1A1PARP1L3MBTL1KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 535 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119977832-A | Benzoyl hydrazine antineoplastic compound and preparation method and application thereof | 江苏海洋大学 | 2025-05-13 | — | — | CN | claimed |
| CN-117402125-A | Preparation method of noo Bo Suan oxadiazole thioester compound, product and application thereof | 南京林业大学 | 2024-01-16 | — | — | CN | claimed |
| CN-109369560-A | Using DMF as one step of carbon source construct 2-(3- chlorphenyl) -1,3,4- oxadiazoles method | 桂林理工大学 | 2019-02-22 | — | — | CN | claimed |
| EP-1392219-A4 | SUBSTITUTED N'-(ARYLCARBONYL)-BENZHYDRAZIDES, N'-(ARYLCARBONYL)-BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOTOSIS AND THE USE THEREOF | CYTOVIA INC (US) | 2007-01-24 | — | — | EP | claimed |
| US-20040186078-A1 | Substituted N'-(arylcarbonyl)-benzhydrazides, N'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2004-09-23 | — | — | US | claimed |
| US-6716859-B2 | ANTICANCER AGENTS | CYTOVIA, INC. | 2004-04-06 | — | — | US | claimed |
| EP-1392219-A2 | SUBSTITUTED N'-(ARYLCARBONYL)-BENZHYDRAZIDES, N'-(ARYLCARBONYL)-BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOTOSIS AND THE USE THEREOF | Cytovia, Inc. (US) | 2004-03-03 | — | — | EP | claimed |
| US-20030105140-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2003-06-05 | — | — | US | claimed |
| US-20030013743-A1 | Substituted N'-(arylcarbonyl)-benzhydrazides, N'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2003-01-16 | — | — | US | claimed |
| WO-2002102301-A2 | SUBSTITUTED INDOLE-2-CARBOXYLIC ACID BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2002-12-27 | — | — | WO | claimed |
| WO-2002089745-A2 | SUBSTITUTED N'-(ARYLCARBONYL)-BENZHYDRAZIDES, N'-(ARYLCARBONYL)-BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2002-11-14 | — | — | WO | claimed |
| US-20020128292-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2002-09-12 | — | — | US | claimed |
| EP-0236646-B1 | ORTHO-ANISAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL APPLICATIONS | Laboratoires DELAGRANGE, Société Anonyme (FR) | 1990-10-10 | — | — | EP | claimed |
| EP-0236646-A1 | Ortho-anisamides, process for their preparation and their pharmaceutical applications | Laboratoires DELAGRANGE, Société Anonyme (FR) | 1987-09-16 | — | — | EP | claimed |
| CN-86105682-A | Novel benzamides, process for their preparation and their use in therapy | — | 1987-02-04 | — | — | CN | claimed |
| US-12478621-B2 | Substituted aminoquinolones as dgkalpha inhibitors for immune activation | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2025-11-25 | — | — | US | disclosed |
| CN-119977832-A | Benzoyl hydrazine antineoplastic compound and preparation method and application thereof | 江苏海洋大学 | 2025-05-13 | — | — | CN | disclosed |
| EP-0080296-A1 | Pharmaceutically active phenyl-thia-, oxa- or triazinones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-06-01 | — | — | EP | disclosed |
| US-4309422-A | INSECTICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| US-4071633-A | Fungicidal N-trichloroacetyl-N'-chlorobenzoylhydrazine derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1978-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128292-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | BAD, API5, CASP2 | KDM4E 2887/4885ALDH1A1 144/4885PARP1 100/4885 |
| US-20030105140-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | BAD, API5, CASP2 | KDM4E 2887/4885ALDH1A1 144/4885PARP1 100/4885 |
| US-20040186078-A1 | Substituted N'-(arylcarbonyl)-benzhydrazides, N'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CASP2, CASP1, BCL2 | KDM4E 2863/4885ALDH1A1 140/4885PARP1 48/4885 |
| US-12478621-B2 | Substituted aminoquinolones as dgkalpha inhibitors for immune activation | DGKK, DGKG, DGKA | KDM4E 1315/4885ALDH1A1 3915/4885PARP1 1779/4885 |
| US-20030013743-A1 | Substituted N'-(arylcarbonyl)-benzhydrazides, N'-(arylcarbonyl)-benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CASP2, CASP1, BCL2 | KDM4E 2863/4885ALDH1A1 140/4885PARP1 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.