Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 15/20 | 0.55 |
| ▸ | ITGB1 | P05556 | 14/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735439 | 0.84 | ITGA4 (0.65) | ITGA4ITGB1ITGB3ITGAVITGA5 | |
| SCHEMBL4735552 | 0.82 | ITGA4 (0.50) | ITGA4ITGB1ITGB3ITGAVITGA5 | |
| SCHEMBL4734610 | 0.82 | ITGA4 (0.61) | ITGA4ITGB1ITGB3ITGAVITGA5 | |
| SCHEMBL4734486 | 0.81 | ITGB1 (0.62) | ITGA4ITGB1ITGB3ITGAVITGA5 | |
| SCHEMBL4736233 | 0.80 | ITGA4 (0.53) | ITGA4ITGB1ITGB3ITGAVITGA5 | |
| SCHEMBL4736103 | 0.78 | ITGA4 (0.62) | ITGA4ITGB1ITGB3ITGAVITGA5 | |
| SCHEMBL4732547 | 0.78 | ITGA4 (0.62) | ITGA4ITGB1ITGB3ITGAVITGA5 | |
| SCHEMBL4736084 | 0.78 | ITGA4 (0.62) | ITGA4ITGB1ITGB3ITGAVITGA5 | |
| SCHEMBL4783431 | 0.77 | ITGA4 (0.59) | ITGA4ITGB1ITGB3ITGAVITGA5 | |
| SCHEMBL4786565 | 0.76 | ITGA4 (0.58) | ITGA4ITGB1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064823-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | claimed |
| WO-2008064823-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | disclosed |