Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737958 | 0.90 | TSHR (0.48) | GAATSHRKDM4ESMOVNN1 | |
| SCHEMBL4736736 | 0.90 | CDK9 (0.44) | GAATSHRKDM4EVNN1OPRM1 | |
| SCHEMBL4735235 | 0.89 | GAA (0.47) | GAATSHRKDM4ESMOOPRM1 | |
| SCHEMBL4735150 | 0.87 | TSHR (0.51) | GAATSHRKDM4ESMN1; SMN2OPRM1 | |
| SCHEMBL4738289 | 0.87 | GAA (0.45) | GAATSHRKDM4ESMOOPRM1 | |
| SCHEMBL4786168 | 0.87 | TSHR (0.47) | GAATSHRKDM4ESMOVNN1 | |
| SCHEMBL3823684 | 0.86 | KDM4E (0.45) | KDM4ELMNAABL1OPRM1OPRK1 | |
| SCHEMBL4736584 | 0.86 | TSHR (0.51) | GAATSHRKDM4ESMN1; SMN2OPRM1 | |
| SCHEMBL4738239 | 0.86 | TSHR (0.49) | GAATSHRKDM4EOPRM1OPRK1 | |
| SCHEMBL4739086 | 0.86 | TSHR (0.52) | GAATSHRKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |