Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9661621 | 0.80 | DRD4 (0.61) | KDM4EALDH1A1SMN1; SMN2ADRB2ADRB1 | |
| SCHEMBL16392408 | 0.78 | KDM4E (0.61) | PPARGKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL5701159 | 0.76 | PPARG (1.00) | PPARGKDM4EMAPK1TDP1KMT2A | |
| SCHEMBL16902851 | 0.75 | TDP1 (0.87) | PPARGKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL10341238 | 0.75 | TDP1 (0.61) | PPARGKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL2671526 | 0.75 | PPARG (0.55) | PPARGKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL16056766 | 0.75 | HRAS (0.56) | PPARGKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL7794296 | 0.74 | DRD2 (0.45) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL470906 | 0.74 | CA12 (0.57) | KDM4EMAPK1TDP1SMN1; SMN2NPC1 | |
| SCHEMBL30541768 | 0.74 | CA12 (0.57) | KDM4EMAPK1TDP1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069518-A1 | PHARMACEUTICAL COMPOSITION FOR CONTROLLING THE FUNCTION OF SPIHNGOSYLPHOSPHORYLCHOLINE | AMOREPACIFIC CORPORATION (KR) | 2008-06-12 | — | — | WO | claimed |
| WO-2008069518-A1 | PHARMACEUTICAL COMPOSITION FOR CONTROLLING THE FUNCTION OF SPIHNGOSYLPHOSPHORYLCHOLINE | AMOREPACIFIC CORPORATION (KR) | 2008-06-12 | — | — | WO | disclosed |
| WO-2007136159-A1 | USE OF SPHINGOSYLPHOSPHORYLCHOLINE ANTAGONIST FOR RESTORING THE EXPRESSION OF ANTIMICROBIAL PEPTIDES | AMOREPACIFIC CORPORATION (KR) | 2007-11-29 | — | — | WO | disclosed |