Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741089 | 0.91 | LMNA (0.44) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4808038 | 0.86 | MAPT (0.48) | L3MBTL1ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL4786641 | 0.85 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4787027 | 0.85 | CYP19A1 (0.55) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4785243 | 0.85 | TP53 (0.48) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4738940 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4738269 | 0.85 | CYP3A4 (0.47) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4738285 | 0.83 | CYP19A1 (0.55) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4740138 | 0.82 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4739848 | 0.82 | NPC1 (0.46) | L3MBTL1ALDH1A1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | disclosed |