SCHEMBL473687

SCHEMBL473687

Cc1ccc2sc3cc(C(=O)O)ccc3c(=O)c2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.46
MCL1 Q07820 1/20 0.46
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 4/20 0.45
HPGD P15428 2/20 0.45
POLB P06746 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA9 Q16790 1/20 0.40
TBXAS1 P24557 2/20 0.40
TTR P02766 2/20 0.39
MAPT P10636 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MAPK1 P28482 1/20 0.39
MAP2K4 P45985 1/20 0.39
MAPKAPK3 Q16644 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL487123 0.99 ALDH1A1 (0.44) BCL2L1MCL1ALDH1A1KDM4EHPGD
SCHEMBL4200676 0.92 ALDH1A1 (0.48) BCL2L1MCL1ALDH1A1KDM4EHPGD
SCHEMBL11240719 0.89 BCL2L1 (0.49) BCL2L1MCL1ALDH1A1KDM4EHPGD
SCHEMBL28456827 0.89 STS (0.45) ALDH1A1KDM4EHPGDSMN1; SMN2NPC1
SCHEMBL487121 0.87 ALDH1A1 (0.47) BCL2L1MCL1ALDH1A1KDM4EHPGD
SCHEMBL28456554 0.86 TTR (0.49) ALDH1A1KDM4EHPGDPOLBSMN1; SMN2
SCHEMBL4541593 0.85 CMA1 (0.48) ALDH1A1KDM4EHPGDPOLBNPC1
SCHEMBL31314634 0.85 CMA1 (0.48) ALDH1A1KDM4EHPGDPOLBNPC1
SCHEMBL14985633 0.84 ALDH1A1 (0.50) BCL2L1MCL1ALDH1A1KDM4EHPGD
SCHEMBL50803 0.82 CA12 (0.44) ALDH1A1KDM4EHPGDPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2477739-B1 PHOTO-LATENT TITANIUM CATALYSTS BASF SE (DE) 2019-04-10 EP disclosed
US-10207261-B2 Photo-latent titanium catalysts BASF SE (DE) 2019-02-19 US disclosed
EP-2203496-B1 PHOTOLATENT CATALYSTS BASED ON ORGANOMETALLIC COMPOUNDS BASF SE (DE) 2018-04-11 EP disclosed
EP-2203496-B1 PHOTOLATENT CATALYSTS BASED ON ORGANOMETALLIC COMPOUNDS BASF SE (DE) 2018-04-11 EP disclosed
EP-1708765-B1 BIOCOMPATIBLE POLYMERIZATION ACCELERATORS SURMODICS INC (US) 2016-08-31 EP disclosed
EP-2638027-B1 LOW-EXTRACTABLE THIOXANTHONES IGM RESINS ITALIA SRL (IT) 2016-07-13 EP disclosed
CN-102497931-B Light is dived titanium catalyst BASF SE (DE) 2016-03-09 CN disclosed
CN-103209974-B Low-extractable thioxanthones LAMBERTI SPA 2015-04-15 CN disclosed
US-8933142-B2 Low-extractable thioxanthones LAMBERTI SPA (IT) 2015-01-13 US disclosed
EP-2638027-A1 LOW-EXTRACTABLE THIOXANTHONES Lamberti SpA (IT) 2013-09-18 EP disclosed
US-6007833-A RESIN MIXTURE HAVING IMPROVED NONTOXICITY, POLYMERIZATION EFFICIENCY, AND SOLUBILITY WHICH FORMS BIODEGRADABLE MATRIX FOR MEDICAL APPLICATION SURMODICS, INC. (US) 1999-12-28 US disclosed
WO-1999047129-A1 CROSSLINKABLE MACROMERS BEARING INITIATOR GROUPS SURMODICS, INC. (US) 1999-09-23 WO disclosed
US-4764584-A Radiation-sensitive polycondensates, their preparation, material coated therewith and the use thereof CIBA-GEIGY CORPORATION (US) 1988-08-16 US disclosed
US-4714669-A POLYAMIDES, POLYESTERS, OR POLYESTER AMIDES CIBA-GEIGY CORPORATION (US) 1987-12-22 US disclosed
US-4656292-A 2,3-dimethylmaleimido-alkyl haloacetates CIBA-GEIGY CORPORATION (US) 1987-04-07 US disclosed
US-4626497-A PHOTOPOLYMERIZABLE ADDITION POLYMER WITH PENDANT MALEIMIDE GROUPS CIBA-GEIGY AG (CH) 1986-12-02 US disclosed
US-4544621-A Photocrosslinkable water-soluble polymers, containing maleimidyl and quaternary ammonium groups process for their preparation and use thereof CIBA GEIGY CORPORATION (US) 1985-10-01 US disclosed
EP-0079307-B1 USE OF PHOTOCROSSLINKABLE COPOLYMERS IN THE MANUFACTURE OF SEMIPERMEABLE MEMBRANES CIBA-GEIGY AG (CH) 1985-08-21 EP disclosed
EP-0079307-A1 Use of photocrosslinkable copolymers in the manufacture of semipermeable membranes CIBA-GEIGY AG (CH) 1983-05-18 EP disclosed
US-4103015-A TRICYCLIC THIOXANTHONE-10,10-DIOXIDES BURROUGHS WELLCOME CO. (US) 1978-07-25 US disclosed