SCHEMBL4736899

SCHEMBL4736899

O=c1[nH]c(=O)n([C@H]2O[C@@H](CO)[C@H](O)[C@H]2F)cc1F

nearest known ligand 0.79

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
TSHR P16473 1/20 0.57
MAPT P10636 1/20 0.57
PMP22 Q01453 1/20 0.57
HBB P68871 1/20 0.57
PYGM P11217 3/20 0.57
TK2 O00142 4/20 0.53
P2RY6 Q15077 2/20 0.53
P2RY14 Q15391 2/20 0.53
NT5E P21589 1/20 0.53
CDA P32320 1/20 0.48
SLC28A1 O00337 1/20 0.48
SLC28A2 O43868 1/20 0.48
SLC29A1 Q99808 1/20 0.48
SLC28A3 Q9HAS3 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21423107 1.00 LMNA (0.59) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL23590367 1.00 LMNA (0.59) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL5968261 1.00 LMNA (0.59) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL10888417 1.00 LMNA (0.59) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL6820201 0.90 LMNA (0.61) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL6820198 0.90 LMNA (0.61) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL6820209 0.90 LMNA (0.61) LMNASMN1; SMN2TSHRMAPTPMP22
5-Fluorouridine SCHEMBL11756887 0.90 PYGM (0.70) LMNASMN1; SMN2TSHRMAPTPMP22
5-Fluorouridine SCHEMBL12174049 0.90 PYGM (0.70) LMNASMN1; SMN2TSHRMAPTPMP22
5-Fluorouridine SCHEMBL21423048 0.90 PYGM (0.70) LMNASMN1; SMN2TSHRMAPTPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008069451-A1 IMPROVED PROCESS FOR THE PREPARATION OF CLEVUDINE AS ANTI-HBV AGENT BUKWANG PHARM CO., LTD. (KR) 2008-06-12 WO disclosed