SCHEMBL6820201

SCHEMBL6820201

O=c1[nH]c(=O)n([C@@H]2O[C@H](CO)[C@@H](F)[C@H]2O)cc1F

nearest known ligand 0.79

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
TSHR P16473 1/20 0.61
MAPT P10636 1/20 0.61
PMP22 Q01453 1/20 0.61
HBB P68871 1/20 0.61
PYGM P11217 3/20 0.57
P2RY6 Q15077 2/20 0.55
P2RY14 Q15391 2/20 0.55
NT5E P21589 1/20 0.55
TK2 O00142 2/20 0.53
SLC28A1 O00337 1/20 0.48
SLC28A2 O43868 1/20 0.48
SLC29A1 Q99808 1/20 0.48
SLC28A3 Q9HAS3 1/20 0.48
P2RY2 P41231 1/20 0.46
DNPH1 O43598 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6820209 1.00 LMNA (0.61) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL6820198 1.00 LMNA (0.61) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL21423107 0.90 LMNA (0.59) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL5968261 0.90 LMNA (0.59) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL10888417 0.90 LMNA (0.59) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL23590367 0.90 LMNA (0.59) LMNASMN1; SMN2TSHRMAPTPMP22
SCHEMBL4736899 0.90 LMNA (0.59) LMNASMN1; SMN2TSHRMAPTPMP22
5-Fluorouridine SCHEMBL11756887 0.90 PYGM (0.70) LMNASMN1; SMN2TSHRMAPTPMP22
5-Fluorouridine SCHEMBL21423048 0.90 PYGM (0.70) LMNASMN1; SMN2TSHRMAPTPMP22
5-Fluorouridine SCHEMBL329381 0.90 PYGM (0.70) LMNASMN1; SMN2TSHRMAPTPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040063651-A1 Remedies for hepatitis c MITSUBISHI PHARMA CORPORATION (JP) 2004-04-01 US claimed
EP-1346724-A1 REMEDIES FOR HEPATITIS C Mitsubishi Pharma Corporation (JP) 2003-09-24 EP claimed
JP-62242624-A None JP disclosed
US-20040063651-A1 Remedies for hepatitis c MITSUBISHI PHARMA CORPORATION (JP) 2004-04-01 US disclosed
EP-1346724-A1 REMEDIES FOR HEPATITIS C Mitsubishi Pharma Corporation (JP) 2003-09-24 EP disclosed
JP-S62242624-A ANTITUMOR AGENT ASAHI GLASS CO LTD 1987-10-23 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063651-A1 Remedies for hepatitis c UPP1, UMPS, UNG LMNA 1944/4885SMN1; SMN2 3112/4885TSHR 3957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.