Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 13/20 | 0.39 |
| ▸ | PPARG | P37231 | 7/20 | 0.39 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14146242 | 0.88 | PTGDR2 (0.33) | PTGDR2PPARAPPARGPPARDHSD11B1 | |
| SCHEMBL4741103 | 0.87 | PPARG (0.42) | PTGDR2PPARAPPARGPPARDUTS2R | |
| SCHEMBL4738549 | 0.83 | PPARG (0.40) | PTGDR2PPARAPPARGPPARD | |
| SCHEMBL4736807 | 0.82 | PTGDR2 (0.43) | PTGDR2PPARAPPARGPPARD | |
| SCHEMBL4739030 | 0.81 | PPARG (0.39) | PTGDR2PPARAPPARGPPARD | |
| SCHEMBL4740249 | 0.81 | PPARG (0.39) | PTGDR2PPARAPPARGPPARDUTS2R | |
| SCHEMBL4739883 | 0.81 | PTGDR2 (0.38) | PTGDR2PPARAPPARGPPARDUTS2R | |
| SCHEMBL4737424 | 0.80 | PPARD (0.46) | PPARAPPARGPPARD | |
| SCHEMBL217980 | 0.76 | PPARA (0.41) | PTGDR2PPARAPPARGPPARD | |
| SCHEMBL14146304 | 0.74 | PPARG (0.36) | PPARAPPARGPPARDUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |