Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.40 |
| ▸ | PPARA | Q07869 | 10/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739030 | 0.92 | PPARG (0.39) | PPARGPPARAFFAR1PPARDPTGDR2 | |
| SCHEMBL4740249 | 0.92 | PPARG (0.39) | PPARGPPARAFFAR1PPARDPTGDR2 | |
| SCHEMBL14146304 | 0.91 | PPARG (0.36) | PPARGPPARAFFAR1PPARDPSEN1 | |
| SCHEMBL4741103 | 0.90 | PPARG (0.42) | PPARGPPARAFFAR1PPARDPTGDR2 | |
| SCHEMBL4739883 | 0.90 | PTGDR2 (0.38) | PPARGPPARAFFAR1PPARDPTGDR2 | |
| SCHEMBL4737403 | 0.83 | PTGDR2 (0.42) | PPARGPPARAPPARDPTGDR2 | |
| SCHEMBL14146648 | 0.83 | FFAR1 (0.35) | PPARGPPARAFFAR1PPARDSLC6A9 | |
| SCHEMBL14146308 | 0.83 | FFAR1 (0.35) | PPARGPPARAFFAR1PPARDSLC6A9 | |
| SCHEMBL14146302 | 0.81 | UTS2R (0.32) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL4736807 | 0.77 | PTGDR2 (0.43) | PPARGPPARAPPARDPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |