Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 10/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738549 | 0.90 | PPARG (0.40) | PPARGFFAR1PTGDR2PPARAPPARD | |
| SCHEMBL4740249 | 0.88 | PPARG (0.39) | PPARGFFAR1PTGDR2PPARAPPARD | |
| SCHEMBL4739030 | 0.88 | PPARG (0.39) | PPARGFFAR1PTGDR2PPARAPPARD | |
| SCHEMBL4737403 | 0.87 | PTGDR2 (0.42) | PPARGPTGDR2PPARAPPARDUTS2R | |
| SCHEMBL4739883 | 0.87 | PTGDR2 (0.38) | PPARGFFAR1PTGDR2PPARAPPARD | |
| SCHEMBL4739586 | 0.81 | PPARD (0.45) | PPARGPPARAPPARD | |
| SCHEMBL14146304 | 0.81 | PPARG (0.36) | PPARGFFAR1PPARAPPARDUTS2R | |
| SCHEMBL4736807 | 0.80 | PTGDR2 (0.43) | PPARGPTGDR2PPARAPPARD | |
| SCHEMBL14146096 | 0.79 | FFAR1 (0.42) | PPARGFFAR1PPARAUTS2RSLC6A9 | |
| SCHEMBL14146648 | 0.78 | FFAR1 (0.35) | PPARGFFAR1PPARAPPARDUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |