Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 11/20 | 0.41 |
| ▸ | PPARG | P37231 | 8/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 8/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14146245 | 0.88 | HRH3 (0.37) | PTGDR2PPARAPPARGHRH3PPARD | |
| SCHEMBL217980 | 0.84 | PPARA (0.41) | PTGDR2PPARAPPARGPPARD | |
| SCHEMBL4737403 | 0.82 | PTGDR2 (0.42) | PTGDR2PPARAPPARGPPARD | |
| SCHEMBL4739636 | 0.82 | PPARA (0.55) | PPARAPPARGPPARDALDH1A1MAPT | |
| SCHEMBL4737303 | 0.81 | PPARA (0.48) | PTGDR2PPARAPPARGPPARDALDH1A1 | |
| SCHEMBL4741103 | 0.80 | PPARG (0.42) | PTGDR2PPARAPPARGPPARD | |
| SCHEMBL4737604 | 0.80 | PPARD (0.45) | PTGDR2PPARAPPARGPPARDMMP1 | |
| SCHEMBL4738549 | 0.77 | PPARG (0.40) | PTGDR2PPARAPPARGPPARD | |
| SCHEMBL4739015 | 0.76 | CYP1A1 (0.50) | PTGDR2 | |
| SCHEMBL4739013 | 0.76 | CYP1A1 (0.50) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |