Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA3 | P34903 | 1/20 | 0.68 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.68 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.68 |
| ▸ | DPP4 | P27487 | 2/20 | 0.63 |
| ▸ | MAOB | P27338 | 5/20 | 0.63 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | F3 | P13726 | 2/20 | 0.57 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | P4HB | P07237 | 1/20 | 0.56 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737429 | 1.00 | GABRA3 (0.68) | GABRA3GABRA2GABRB2DPP4MAOB | |
| SCHEMBL4739000 | 0.84 | MAPT (0.51) | GABRA3GABRA2GABRB2DPP4MAOB | |
| SCHEMBL4738997 | 0.84 | MAPT (0.51) | GABRA3GABRA2GABRB2DPP4MAOB | |
| SCHEMBL4736818 | 0.83 | GABRA3 (0.47) | GABRA3GABRA2GABRB2DPP4MAOB | |
| SCHEMBL4736824 | 0.83 | GABRA3 (0.47) | GABRA3GABRA2GABRB2DPP4MAOB | |
| SCHEMBL4139154 | 0.81 | GABRA3 (0.78) | GABRA3GABRA2GABRB2DPP4MAOB | |
| SCHEMBL4785911 | 0.81 | DPP4 (0.55) | GABRA3GABRA2GABRB2DPP4MAOB | |
| SCHEMBL28339980 | 0.81 | GABRA3 (0.78) | GABRA3GABRA2GABRB2DPP4MAOB | |
| SCHEMBL4785916 | 0.81 | DPP4 (0.55) | GABRA3GABRA2GABRB2DPP4MAOB | |
| SCHEMBL4741105 | 0.81 | MAPT (0.56) | MAOBMAPTLMNARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |