Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736824 | 1.00 | GABRA3 (0.47) | GABRA3GABRA2GABRB2DPP4CYP1A1 | |
| SCHEMBL4741756 | 0.83 | GABRA3 (0.48) | GABRA3GABRA2GABRB2CYP1A1CYP1B1 | |
| SCHEMBL4741758 | 0.83 | GABRA3 (0.48) | GABRA3GABRA2GABRB2CYP1A1CYP1B1 | |
| SCHEMBL4737428 | 0.83 | GABRA3 (0.68) | GABRA3GABRA2GABRB2DPP4MAPT | |
| SCHEMBL4737429 | 0.83 | GABRA3 (0.68) | GABRA3GABRA2GABRB2DPP4MAPT | |
| SCHEMBL4737441 | 0.83 | CYP1A1 (0.58) | DPP4CYP1A1CYP1B1MAPTMAPK1 | |
| SCHEMBL4737444 | 0.83 | CYP1A1 (0.58) | DPP4CYP1A1CYP1B1MAPTMAPK1 | |
| SCHEMBL217753 | 0.81 | ERCC5 (0.47) | MAOBCYP2D6 | |
| SCHEMBL217754 | 0.81 | ERCC5 (0.47) | MAOBCYP2D6 | |
| SCHEMBL4738997 | 0.81 | MAPT (0.51) | GABRA3GABRA2GABRB2DPP4CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |