Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739000 | 1.00 | MAPT (0.51) | MAPTMAPK1ALDH1A1MAOBHSP90AA1 | |
| SCHEMBL4737429 | 0.84 | GABRA3 (0.68) | MAPTALDH1A1MAOBRAB9AGABRA3 | |
| SCHEMBL4737428 | 0.84 | GABRA3 (0.68) | MAPTALDH1A1MAOBRAB9AGABRA3 | |
| SCHEMBL4736824 | 0.81 | GABRA3 (0.47) | MAPTMAPK1MAOBHSP90AA1CAPN1 | |
| SCHEMBL4736818 | 0.81 | GABRA3 (0.47) | MAPTMAPK1MAOBHSP90AA1CAPN1 | |
| SCHEMBL4785916 | 0.79 | DPP4 (0.55) | MAPTMAPK1MAOBHSP90AA1RAB9A | |
| SCHEMBL4785911 | 0.79 | DPP4 (0.55) | MAPTMAPK1MAOBHSP90AA1RAB9A | |
| SCHEMBL4741100 | 0.79 | PPARG (0.46) | MAPTALDH1A1MAOBHSP90AA1NPC1 | |
| SCHEMBL4740248 | 0.79 | PPARG (0.46) | MAPTALDH1A1MAOBHSP90AA1NPC1 | |
| SCHEMBL4741105 | 0.76 | MAPT (0.56) | MAPTMAPK1ALDH1A1MAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |