Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.35 |
| ▸ | ITGAV | P06756 | 10/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665336 | 0.84 | CHRM5 (0.36) | — | |
| SCHEMBL4786490 | 0.84 | TNKS (0.42) | ALDH1A1TNKSPARP1PARP2 | |
| SCHEMBL3808537 | 0.83 | CACNA1G (0.34) | — | |
| SCHEMBL4731396 | 0.82 | KCNH2 (0.40) | ITGB3ITGAVKCNH2ALDH1A1GRIN2B | |
| SCHEMBL4737981 | 0.81 | CACNA1G (0.33) | — | |
| SCHEMBL3665443 | 0.80 | RXFP1 (0.36) | ALDH1A1 | |
| SCHEMBL3667342 | 0.80 | CHRM1 (0.34) | KCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL3671643 | 0.78 | CHRM5 (0.39) | ALDH1A1GAA | |
| SCHEMBL4735430 | 0.78 | CACNA1G (0.35) | GAA | |
| SCHEMBL3668869 | 0.77 | BCHE (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | claimed |