Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | HTT | P42858 | 1/20 | 0.76 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LSS | P48449 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21091969 | 0.92 | ALDH1A1 (0.88) | ALDH1A1KDM4EHTTCA2LMNA | |
| Hydrochloric Acid SCHEMBL28938255 | 0.91 | ALDH1A1 (0.85) | ALDH1A1KDM4EHTTCA2LMNA | |
| SCHEMBL30828559 | 0.88 | ALDH1A1 (0.80) | ALDH1A1KDM4EHTTCA2HDAC4 | |
| SCHEMBL6077802 | 0.87 | L3MBTL1 (0.77) | ALDH1A1CA2LMNAHDAC1HDAC6 | |
| SCHEMBL3919500 | 0.86 | ALDH1A1 (0.78) | ALDH1A1KDM4EHTTCA2LMNA | |
| SCHEMBL3816827 | 0.85 | LMNA (0.63) | ALDH1A1KDM4EHTTLMNAL3MBTL1 | |
| SCHEMBL2701620 | 0.85 | ALDH1A1 (0.76) | ALDH1A1KDM4EHTTCA2LMNA | |
| SCHEMBL2701623 | 0.85 | ALDH1A1 (0.76) | ALDH1A1KDM4EHTTCA2LMNA | |
| Hydrochloric Acid SCHEMBL4736121 | 0.84 | LMNA (0.62) | ALDH1A1KDM4EHTTLMNAL3MBTL1 | |
| SCHEMBL3058881 | 0.84 | ALDH1A1 (0.74) | ALDH1A1KDM4EHTTCA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |