Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | KDR | P35968 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259979 | 0.89 | GAA (0.72) | GAAMAPTCYP3A4KDRSMN1; SMN2 | |
| SCHEMBL9575221 | 0.86 | CYP3A4 (0.56) | GAAMAPTCYP3A4KDRSMN1; SMN2 | |
| Aminosalicylic Acid SCHEMBL28180521 | 0.84 | ALDH1A1 (0.76) | GAAMAPTCYP3A4KDRSMN1; SMN2 | |
| SCHEMBL29741471 | 0.84 | GAA (0.66) | GAAMAPTCYP3A4KDRSMN1; SMN2 | |
| SCHEMBL27642838 | 0.84 | GAA (0.66) | GAAMAPTCYP3A4KDRSMN1; SMN2 | |
| SCHEMBL9949356 | 0.84 | GAA (0.66) | GAAMAPTCYP3A4KDRSMN1; SMN2 | |
| SCHEMBL15872185 | 0.83 | GAA (0.61) | GAAMAPTCYP3A4KDRSMN1; SMN2 | |
| SCHEMBL616715 | 0.81 | GAA (1.00) | GAAMAPTCYP3A4KDRSMN1; SMN2 | |
| SCHEMBL5306078 | 0.81 | GAA (0.63) | GAAMAPTCYP3A4KDRSMN1; SMN2 | |
| SCHEMBL20594758 | 0.80 | GAA (0.61) | GAAMAPTCYP3A4KDRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5086279-A | — | — | None | — | — | JP | disclosed |
| CN-106573065-A | Methods for treating inflammatory bowel disease | 诺格尔制药有限公司 | 2017-04-19 | — | — | CN | disclosed |
| WO-2008085484-A2 | TREATMENT OF INFLAMMATORY BOWEL DISEASE WITH ENTERIC COATED FORMULATIONS COMPRISING 5-AMINOSALICYLIC ACID OR 4-AMINOSALICYLIC ACID | JACOBUS PHARMACEUTICAL COMPANY, INC. (US) | 2008-07-17 | — | — | WO | disclosed |
| JP-H0586279-A | PRODUCTION OF ANHYDRIDE-CAPPED POLYPHENYLENE ETHER BY MELT PROCESS | GENERAL ELECTRIC CO <GE> | 1993-04-06 | — | — | JP | disclosed |