SCHEMBL9949356

SCHEMBL9949356

NC(=O)OC(=O)c1ccc(N)cc1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.66
MAPT P10636 4/20 0.58
CYP3A4 P08684 3/20 0.58
KDR P35968 2/20 0.58
LMNA P02545 1/20 0.58
TP53 P04637 1/20 0.58
ADORA3 P0DMS8 1/20 0.58
CHRM1 P11229 1/20 0.58
TBXA2R P21731 1/20 0.58
SLC6A2 P23975 1/20 0.58
PDE4A P27815 1/20 0.58
ADRA1A P35348 1/20 0.58
SLC6A3 Q01959 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
ALDH1A1 P00352 5/20 0.58
KDM4E B2RXH2 4/20 0.58
ESR2 Q92731 1/20 0.58
PTPN1 P18031 1/20 0.58
TDP1 Q9NUW8 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1259979 0.90 GAA (0.72) GAAMAPTCYP3A4KDRLMNA
SCHEMBL27642838 0.85 GAA (0.66) GAAMAPTCYP3A4KDRLMNA
SCHEMBL29741471 0.85 GAA (0.66) GAAMAPTCYP3A4KDRLMNA
SCHEMBL4737522 0.84 GAA (0.69) GAAMAPTCYP3A4KDRLMNA
SCHEMBL27447975 0.83 MAPT (0.44) GAAMAPTCYP3A4KDRLMNA
SCHEMBL19168585 0.81 GAA (0.70) GAAMAPTCYP3A4KDRLMNA
SCHEMBL9949713 0.80 ADRB2 (0.47) GAAMAPTCYP3A4KDRLMNA
SCHEMBL9949895 0.80 CHRM2 (0.51) GAAMAPTCYP3A4KDRLMNA
SCHEMBL9949367 0.80 GAA (0.42) GAAMAPTCYP3A4KDRLMNA
SCHEMBL5306078 0.80 GAA (0.63) GAAMAPTCYP3A4KDRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120165315-A1 MEPTAZINOL CARBAMATE PRODRUG SALTS JOSTENS, INC. 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165315-A1 MEPTAZINOL CARBAMATE PRODRUG SALTS MEP1A, MEP1B, CTSZ GAA 2355/4885MAPT 953/4885CYP3A4 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.