Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | TNF | P01375 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL596783 | 0.89 | ALDH1A1 (0.64) | CYP3A4KDM4EALDH1A1TDP1KDR | |
| SCHEMBL4737522 | 0.86 | GAA (0.69) | CYP3A4KDM4EALDH1A1TDP1KDR | |
| SCHEMBL29448242 | 0.81 | GAA (0.73) | CYP3A4KDM4EALDH1A1TDP1KDR | |
| SCHEMBL5267852 | 0.81 | CA12 (0.67) | CYP3A4KDM4EALDH1A1TDP1MEN1 | |
| SCHEMBL267165 | 0.81 | GAA (0.73) | CYP3A4KDM4EALDH1A1TDP1KDR | |
| SCHEMBL5032667 | 0.81 | GAA (0.41) | CYP3A4KDM4EALDH1A1TDP1KDR | |
| SCHEMBL22630592 | 0.79 | KDM4E (0.62) | CYP3A4KDM4EALDH1A1TDP1KDR | |
| SCHEMBL19169377 | 0.79 | ALDH1A1 (0.62) | CYP3A4KDM4EALDH1A1TDP1KDR | |
| SCHEMBL9318003 | 0.79 | CFD (0.47) | CYP3A4KDM4EALDH1A1TDP1KDR | |
| SCHEMBL29526665 | 0.79 | KDM4E (0.67) | CYP3A4KDM4EALDH1A1TDP1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5086279-A | — | — | None | — | — | JP | disclosed |
| JP-H0586279-A | PRODUCTION OF ANHYDRIDE-CAPPED POLYPHENYLENE ETHER BY MELT PROCESS | GENERAL ELECTRIC CO <GE> | 1993-04-06 | — | — | JP | disclosed |