Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.73 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | STAT3 | P40763 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.65 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769978 | 0.90 | MAPT (0.70) | KCNQ3KCNQ2MAPTSMN1; SMN2STAT3 | |
| SCHEMBL4251030 | 0.88 | MAPT (0.86) | KCNQ3KCNQ2MAPTSMN1; SMN2STAT3 | |
| SCHEMBL4247738 | 0.88 | MAPT (0.86) | KCNQ3KCNQ2MAPTSMN1; SMN2STAT3 | |
| SCHEMBL4257469 | 0.86 | KCNQ3 (0.65) | KCNQ3KCNQ2MAPTSMN1; SMN2STAT3 | |
| SCHEMBL3058918 | 0.85 | RAB9A (0.72) | KCNQ3KCNQ2MAPTSMN1; SMN2STAT3 | |
| SCHEMBL4738294 | 0.85 | HDAC2 (0.67) | KCNQ3KCNQ2MAPTSMN1; SMN2STAT3 | |
| SCHEMBL3461764 | 0.85 | MAPT (0.64) | KCNQ3KCNQ2MAPTSMN1; SMN2STAT3 | |
| Hydrochloric Acid SCHEMBL3826978 | 0.84 | RAB9A (0.71) | KCNQ3KCNQ2MAPTSMN1; SMN2STAT3 | |
| SCHEMBL4250462 | 0.84 | MAPT (0.67) | KCNQ3KCNQ2MAPTSMN1; SMN2STAT3 | |
| SCHEMBL3063610 | 0.83 | ALDH1A1 (0.60) | KCNQ3KCNQ2MAPTSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |