Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 4/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.58 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.58 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13553093 | 0.88 | RAB9A (0.65) | HDAC2HDAC3HDAC1HDAC10HDAC6 | |
| SCHEMBL403550 | 0.87 | HDAC2 (0.64) | HDAC2HDAC3HDAC1HDAC10HDAC6 | |
| SCHEMBL4968097 | 0.86 | HDAC2 (0.60) | HDAC2HDAC3HDAC1HDAC10HDAC6 | |
| SCHEMBL4737529 | 0.85 | KCNQ3 (0.73) | HDAC10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3058918 | 0.85 | RAB9A (0.72) | HDAC2HDAC3HDAC10CYP1A2CYP3A4 | |
| SCHEMBL2301605 | 0.85 | SMN1; SMN2 (0.55) | HDAC2HDAC3HDAC6CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL3826978 | 0.84 | RAB9A (0.71) | HDAC2HDAC3HDAC10CYP1A2CYP3A4 | |
| SCHEMBL3063610 | 0.83 | ALDH1A1 (0.60) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8325360 | 0.82 | KCNH2 (0.52) | HDAC2HDAC3HDAC1HDAC10HDAC6 | |
| SCHEMBL21905464 | 0.81 | HDAC1 (0.79) | HDAC2HDAC3HDAC1HDAC10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |