Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 7/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.44 |
| ▸ | ITGAL | P20701 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3717023 | 0.98 | BACE1 (0.49) | BACE1GAAITGB2ICAM1ITGAL | |
| SCHEMBL14333527 | 0.84 | CES2 (0.50) | BACE1ITGB2ICAM1ITGALKMT2A | |
| Hydrochloric Acid SCHEMBL320643 | 0.82 | CES2 (0.48) | BACE1ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL22790324 | 0.81 | GAA (0.47) | BACE1GAAJAK2JAK1TYK2 | |
| SCHEMBL791513 | 0.81 | GAA (0.47) | BACE1GAAITGB2ICAM1ITGAL | |
| SCHEMBL2867748 | 0.79 | PBRM1 (0.58) | GAAITGB2ICAM1ITGALPBRM1 | |
| Hydrochloric Acid SCHEMBL15568289 | 0.78 | PBRM1 (0.56) | GAAITGB2ICAM1ITGALPBRM1 | |
| Iodide SCHEMBL5204408 | 0.78 | GAA (0.45) | BACE1GAAJAK2JAK1TYK2 | |
| SCHEMBL1780411 | 0.77 | TSHR (0.48) | BACE1TAAR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7952512 | 0.77 | CES2 (0.43) | BACE1ITGB2ICAM1ITGALJAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |