Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17329160 | 0.78 | ALDH1A1 (0.52) | TSHRALDH1A1CA1CA2CA12 | |
| Hydrochloric Acid SCHEMBL8376644 | 0.77 | TSHR (0.44) | TSHRALDH1A1F2PLAUPLAT | |
| SCHEMBL4737570 | 0.77 | BACE1 (0.50) | ALDH1A1LMNATAAR1BACE1KMT2A | |
| SCHEMBL10495291 | 0.76 | ALDH1A1 (0.41) | TSHRALDH1A1CA1CA2CA12 | |
| Hydrochloric Acid SCHEMBL3717023 | 0.75 | BACE1 (0.49) | ALDH1A1LMNATAAR1BACE1KMT2A | |
| 2-Chlorophenol SCHEMBL28465787 | 0.75 | ALDH1A1 (0.75) | TSHRALDH1A1CA1CA2CA12 | |
| Hydrochloric Acid SCHEMBL8378249 | 0.74 | ALOX15 (0.46) | TSHRALDH1A1CA1CA2CA12 | |
| Hydrochloric Acid SCHEMBL8596256 | 0.72 | CA2 (0.37) | ALDH1A1CA1CA2CA12CA7 | |
| SCHEMBL330729 | 0.71 | CA12 (0.70) | TSHRALDH1A1CA1CA2CA12 | |
| SCHEMBL10495289 | 0.71 | KDM4E (0.57) | TSHRALDH1A1CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173641-B2 | 4-amino-1,2,3-benzoxathiazine-derivatives as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8173641-B2 | 4-amino-1,2,3-benzoxathiazine-derivatives as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8173641-B2 | 4-amino-1,2,3-benzoxathiazine-derivatives as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-05-08 | — | — | US | disclosed |
| CN-102317271-A | 4-Amino-1,2,3-benzoxathiazine-derivatives as pesticides | BAYER CROPSCIENCE AG | 2012-01-11 | — | — | CN | disclosed |
| EP-2376465-A1 | 4-AMINO-1,2,3- BENZOXATHIAZINE DERIVATIVES AS PESTICIDES | Bayer CropScience AG (DE) | 2011-10-19 | — | — | EP | disclosed |
| US-20110118240-A2 | 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20110118240-A2 | 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20110118240-A2 | 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20100267703-A1 | 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2010-10-21 | — | — | US | disclosed |
| US-20100267703-A1 | 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2010-10-21 | — | — | US | disclosed |
| US-20100267703-A1 | 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2010-10-21 | — | — | US | disclosed |
| WO-2010072310-A1 | 4-AMINO-1,2,3- BENZOXATHIAZINE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010072310-A1 | 4-AMINO-1,2,3- BENZOXATHIAZINE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-07-01 | — | — | WO | disclosed |
| EP-2196461-A1 | 4-Amino-1,2,3-benzoxathiazine-derivatives as pesticides | Bayer CropScience AG (DE) | 2010-06-16 | — | — | EP | disclosed |
| EP-2196461-A1 | 4-Amino-1,2,3-benzoxathiazine-derivatives as pesticides | Bayer CropScience AG (DE) | 2010-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267703-A1 | 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides | P2RX5, SLC1A5, P2RX4 | TSHR 1443/4885ALDH1A1 2671/4885CA1 713/4885 |
| US-20110118240-A2 | 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides | P2RX5, P2RX4, SLC1A5 | TSHR 1290/4885ALDH1A1 2519/4885CA1 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.