Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 7/20 | 0.59 |
| ▸ | CA1 | P00915 | 5/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18838 | 0.79 | GAA (0.67) | LMNACA2CA1CA12CA9 | |
| SCHEMBL8028971 | 0.79 | LMNA (0.65) | LMNACA2CA1CA12CA9 | |
| SCHEMBL3792342 | 0.79 | GAA (0.67) | LMNACA2CA1CA12CA9 | |
| SCHEMBL29724901 | 0.79 | GAA (0.67) | LMNACA2CA1CA12CA9 | |
| SCHEMBL547730 | 0.79 | LMNA (0.65) | LMNACA2CA1CA12CA9 | |
| SCHEMBL124022 | 0.79 | GAA (0.67) | LMNACA2CA1CA12CA9 | |
| Hydrochloric Acid SCHEMBL10624747 | 0.77 | GAA (0.64) | LMNACA2CA1CA12CA9 | |
| SCHEMBL21095944 | 0.77 | LMNA (0.62) | LMNACA2CA1CA12CA9 | |
| Phenolsulfonic Acid SCHEMBL18275 | 0.77 | LMNA (1.00) | LMNACA2CA1CA12CA9 | |
| Water SCHEMBL6425932 | 0.77 | GAA (0.64) | LMNACA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847568-B1 | THERMOSETTING RESIN COMPOSITION, THERMOSETTING-RESIN MOLDING MATERIAL, AND CURED OBJECT OBTAINED THEREFROM | SUMITOMO BAKELITE CO (JP) | 2015-05-20 | — | — | EP | claimed |
| CN-101993416-A | Quinoline compound and preparation method thereof, medicament combination containing compound and application of compound | SHANGHAI INST MATERIA MEDICA | 2011-03-30 | — | — | CN | claimed |
| EP-1847568-B1 | THERMOSETTING RESIN COMPOSITION, THERMOSETTING-RESIN MOLDING MATERIAL, AND CURED OBJECT OBTAINED THEREFROM | SUMITOMO BAKELITE CO (JP) | 2015-05-20 | — | — | EP | disclosed |
| CN-101993416-B | Quinoline compound and preparation method thereof, medicament combination containing compound and application of compound | SHANGHAI INST MATERIA MEDICA | 2013-09-11 | — | — | CN | disclosed |
| CN-101993416-A | Quinoline compound and preparation method thereof, medicament combination containing compound and application of compound | SHANGHAI INST MATERIA MEDICA | 2011-03-30 | — | — | CN | disclosed |
| WO-2008076826-A1 | PYROPHOSPHORAMIDE ALKYLATORS | THRESHOLD PHARMACEUTICALS, INC. (US) | 2008-06-26 | — | — | WO | disclosed |