Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737615 | 1.00 | MAOB (0.44) | MAOBP4HBABCG2ARNFKB1 | |
| SCHEMBL4736739 | 0.80 | MAOB (0.45) | MAOBLMNAGAAMAPTATM | |
| SCHEMBL4736741 | 0.80 | MAOB (0.45) | MAOBLMNAGAAMAPTATM | |
| SCHEMBL4737441 | 0.73 | CYP1A1 (0.58) | MAOBP4HBABCG2MAPT | |
| SCHEMBL4737444 | 0.73 | CYP1A1 (0.58) | MAOBP4HBABCG2MAPT | |
| SCHEMBL4739838 | 0.71 | CYP1A1 (0.49) | MAOBP4HBCHRNA7MAPT | |
| SCHEMBL14146272 | 0.71 | CHRNA7 (0.40) | CHRNA7CTSS | |
| SCHEMBL4739835 | 0.71 | CYP1A1 (0.49) | MAOBP4HBCHRNA7MAPT | |
| SCHEMBL31552798 | 0.71 | BCHE (0.69) | MAOBP4HBABCG2ARNFKB1 | |
| SCHEMBL219717 | 0.70 | HDAC6 (0.43) | MAOBP4HBMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |