Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 15/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 15/20 | 0.58 |
| ▸ | DPP4 | P27487 | 1/20 | 0.58 |
| ▸ | P4HB | P07237 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737444 | 1.00 | CYP1A1 (0.58) | CYP1A1CYP1B1DPP4P4HBMAOB | |
| SCHEMBL4739835 | 0.83 | CYP1A1 (0.49) | CYP1A1CYP1B1DPP4P4HBMAOB | |
| SCHEMBL4739838 | 0.83 | CYP1A1 (0.49) | CYP1A1CYP1B1DPP4P4HBMAOB | |
| SCHEMBL4736818 | 0.83 | GABRA3 (0.47) | CYP1A1CYP1B1DPP4P4HBMAOB | |
| SCHEMBL4736824 | 0.83 | GABRA3 (0.47) | CYP1A1CYP1B1DPP4P4HBMAOB | |
| SCHEMBL4785911 | 0.81 | DPP4 (0.55) | CYP1B1DPP4MAOBCXCL12MAPT | |
| SCHEMBL4785916 | 0.81 | DPP4 (0.55) | CYP1B1DPP4MAOBCXCL12MAPT | |
| SCHEMBL219914 | 0.80 | MAOA (0.51) | CYP1A1CYP1B1DPP4P4HBMAOB | |
| SCHEMBL219196 | 0.80 | MAOA (0.46) | CYP1A1CYP1B1DPP4P4HBMAOB | |
| SCHEMBL219913 | 0.80 | MAOA (0.51) | CYP1A1CYP1B1DPP4P4HBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |