Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 9/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 9/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | P4HB | P07237 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739838 | 1.00 | CYP1A1 (0.49) | CYP1A1CYP1B1DPP4CXCL12MAOB | |
| SCHEMBL4737441 | 0.83 | CYP1A1 (0.58) | CYP1A1CYP1B1DPP4CXCL12MAOB | |
| SCHEMBL4737444 | 0.83 | CYP1A1 (0.58) | CYP1A1CYP1B1DPP4CXCL12MAOB | |
| SCHEMBL14146094 | 0.81 | CHRNA7 (0.39) | CYP1A1CYP1B1DPP4CXCL12MAPT | |
| SCHEMBL4736808 | 0.80 | TNFRSF1A (0.46) | CYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4736804 | 0.80 | TNFRSF1A (0.46) | CYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4736818 | 0.72 | GABRA3 (0.47) | CYP1A1CYP1B1DPP4MAOBP4HB | |
| SCHEMBL4736824 | 0.72 | GABRA3 (0.47) | CYP1A1CYP1B1DPP4MAOBP4HB | |
| SCHEMBL216812 | 0.71 | MAOA (0.42) | CYP1A1CYP1B1DPP4CXCL12MAOB | |
| SCHEMBL216811 | 0.71 | MAOA (0.42) | CYP1A1CYP1B1DPP4CXCL12MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |