Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 12/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.44 |
| ▸ | PGR | P06401 | 5/20 | 0.44 |
| ▸ | AR | P10275 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737727 | 0.87 | NR3C1 (0.44) | SMONR3C1PGRAR | |
| SCHEMBL4733246 | 0.80 | NR3C1 (0.49) | SMONR3C1PGRAR | |
| SCHEMBL4737738 | 0.79 | NR3C1 (0.65) | NR3C1PGRAR | |
| SCHEMBL4736670 | 0.67 | NR3C1 (0.41) | SMONR3C1PGRAR | |
| SCHEMBL1360932 | 0.67 | SMO (0.61) | SMONR3C1PGR | |
| SCHEMBL4733244 | 0.67 | NR3C1 (0.47) | SMONR3C1PGRAR | |
| SCHEMBL4325784 | 0.67 | NR3C1 (0.68) | SMONR3C1PGR | |
| SCHEMBL4277603 | 0.66 | NR3C1 (0.52) | SMONR3C1PGR | |
| SCHEMBL14144313 | 0.65 | NR3C1 (0.37) | NR3C1PGRAR | |
| SCHEMBL4552036 | 0.63 | NR3C1 (0.53) | SMONR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079073-A1 | INDAZOLYL SULPHONAMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS | ASTRAZENECA AB (SE) | 2008-07-03 | — | — | WO | disclosed |