Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 4/20 | 0.61 |
| ▸ | CDC25A | P30304 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737756 | 0.90 | CDC25B (0.55) | CDC25BCDC25AHSD17B10ALDH1A1AKR1C3 | |
| SCHEMBL4737753 | 0.88 | HSD17B10 (0.44) | CDC25BCDC25AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL17864530 | 0.80 | RXRB (0.47) | HSD17B10ALDH1A1KDM4EATMTDP1 | |
| SCHEMBL30638610 | 0.80 | KDM4E (0.50) | CDC25BCDC25AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL17713226 | 0.80 | KDM4E (0.50) | CDC25BCDC25AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL27534696 | 0.80 | KDM4E (0.46) | CDC25BCDC25AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL8175787 | 0.79 | SLC7A5 (0.42) | CDC25BCDC25AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL722115 | 0.79 | ALDH1A1 (0.56) | HSD17B10ALDH1A1AKR1C3KDM4ELMNA | |
| SCHEMBL30339401 | 0.79 | ALDH1A1 (0.56) | HSD17B10ALDH1A1AKR1C3KDM4ELMNA | |
| SCHEMBL1367340 | 0.78 | GABRA1 (0.43) | ALDH1A1TDP1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060844-A1 | POLYMERIZATION INHIBITOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE | ALBEMARLE CORPORATION (US) | 2008-05-22 | — | — | WO | disclosed |