SCHEMBL17864530

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1367340	0.88	GABRA1 (0.43)	RXRBGABRA1GABRG2GABRB3GABRA3
	SCHEMBL14785529	0.86	MYC (0.44)	RXRBCA12CA1CA2CA9
	SCHEMBL8492434	0.85	CA12 (0.47)	GABRA1GABRG2GABRB3GABRA3GABRA2
	SCHEMBL13948752	0.84	GABRA1 (0.48)	GABRA1GABRG2GABRB3GABRA3GABRA2
	SCHEMBL1251557	0.83	ALDH1A1 (0.54)	GABRA1GABRG2GABRB3GABRA3GABRA2
	SCHEMBL5783893	0.83	TSHR (0.49)	GABRA1GABRG2GABRB3GABRA3GABRA2
	SCHEMBL27905930	0.83	GABRA1 (0.46)	GABRA1GABRG2GABRB3GABRA3GABRA2
	SCHEMBL17864532	0.83	NR1H4 (0.47)	GABRA1GABRG2GABRB3GABRA3GABRA2
	SCHEMBL7401464	0.82	ALDH1A1 (0.53)	GABRA1GABRG2GABRB3GABRA3GABRA2
	SCHEMBL8845140	0.82	GABRA1 (0.42)	GABRA1GABRG2GABRB3GABRA3GABRA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.