Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14068758 | 0.86 | — | — | |
| SCHEMBL4735036 | 0.84 | CNR1 (0.36) | — | |
| SCHEMBL4737057 | 0.81 | OPRL1 (0.36) | — | |
| SCHEMBL4737019 | 0.81 | BACE1 (0.31) | — | |
| SCHEMBL4734073 | 0.80 | CHIA (0.33) | BRD4NR3C1 | |
| SCHEMBL4736369 | 0.80 | PIN1 (0.30) | — | |
| SCHEMBL4738895 | 0.80 | KMT2A (0.36) | — | |
| SCHEMBL4739803 | 0.77 | — | — | |
| SCHEMBL4740444 | 0.76 | HCAR2 (0.34) | — | |
| SCHEMBL4737642 | 0.76 | NPY5R (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071765-A1 | PHARMACEUTICALLY ACTIVE SPIRO-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2008-06-19 | — | — | WO | claimed |