Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 10/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735036 | 0.88 | CNR1 (0.36) | GRIN2B | |
| SCHEMBL14068758 | 0.83 | — | — | |
| SCHEMBL4739255 | 0.81 | CHRM2 (0.35) | RORCHCRTR1HCRTR2SPR | |
| SCHEMBL4737833 | 0.81 | BRD4 (0.31) | — | |
| SCHEMBL4736369 | 0.77 | PIN1 (0.30) | — | |
| SCHEMBL4738064 | 0.77 | AVPR1A (0.34) | SPR | |
| SCHEMBL4783797 | 0.76 | RORC (0.38) | RORC | |
| SCHEMBL4737352 | 0.75 | LMNA (0.33) | — | |
| SCHEMBL4739803 | 0.75 | — | — | |
| SCHEMBL4740444 | 0.74 | HCAR2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071765-A1 | PHARMACEUTICALLY ACTIVE SPIRO-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2008-06-19 | — | — | WO | claimed |