Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739803 | 0.91 | — | — | |
| SCHEMBL14068758 | 0.90 | — | — | |
| SCHEMBL4735029 | 0.89 | NPY5R (0.33) | KDM4E | |
| SCHEMBL4737352 | 0.88 | LMNA (0.33) | — | |
| SCHEMBL4738952 | 0.87 | — | — | |
| SCHEMBL4736369 | 0.85 | PIN1 (0.30) | — | |
| SCHEMBL4736353 | 0.84 | HRH3 (0.32) | — | |
| SCHEMBL14068756 | 0.82 | — | — | |
| SCHEMBL4739249 | 0.80 | PIN1 (0.31) | — | |
| SCHEMBL4782354 | 0.79 | KDM4E (0.32) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071765-A1 | PHARMACEUTICALLY ACTIVE SPIRO-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2008-06-19 | — | — | WO | claimed |