Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739107 | 0.91 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL4738609 | 0.89 | DHODH (0.36) | KDM4EALDH1A1KMT2A | |
| SCHEMBL4735029 | 0.87 | NPY5R (0.33) | KDM4EALDH1A1 | |
| SCHEMBL4739802 | 0.86 | NPC1 (0.32) | — | |
| SCHEMBL4734384 | 0.85 | KMT2A (0.36) | ALDH1A1GLAKMT2A | |
| SCHEMBL4737070 | 0.85 | ALDH1A1 (0.36) | KDM4EALDH1A1GLAKMT2A | |
| SCHEMBL14068756 | 0.84 | — | — | |
| SCHEMBL4734073 | 0.84 | CHIA (0.33) | KDM4E | |
| SCHEMBL13983102 | 0.83 | HRH3 (0.31) | — | |
| SCHEMBL4737882 | 0.83 | RAB9A (0.35) | KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071765-A1 | PHARMACEUTICALLY ACTIVE SPIRO-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2008-06-19 | — | — | WO | claimed |