Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | FASN | P49327 | 8/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4199218 | 0.87 | PARP10 (0.47) | PARP10PARP14FASNNAMPTALDH1A1 | |
| SCHEMBL4738174 | 0.84 | FASN (0.52) | FASN | |
| SCHEMBL4203212 | 0.81 | FASN (0.53) | FASN | |
| SCHEMBL4196829 | 0.81 | P2RY14 (0.45) | FASNEGLN1LMNA | |
| SCHEMBL4738617 | 0.81 | PARP10 (0.45) | PARP10PARP14FASNNAMPTALDH1A1 | |
| SCHEMBL4739507 | 0.81 | FASN (0.52) | FASN | |
| SCHEMBL4207436 | 0.81 | FASN (0.52) | FASN | |
| SCHEMBL4205017 | 0.80 | FASN (0.53) | FASN | |
| SCHEMBL4203136 | 0.80 | FASN (0.51) | FASN | |
| SCHEMBL4209385 | 0.79 | FASN (0.49) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075064-A1 | PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |