Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.82 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.82 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.82 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.53 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.53 |
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | KDM5C | P41229 | 4/20 | 0.43 |
| ▸ | KDM6B | O15054 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alpha-Ketoglutaric Acid SCHEMBL1966431 | 0.92 | EGLN1 (0.78) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL30208560 | 0.91 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL30029036 | 0.91 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL3776640 | 0.91 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL932116 | 0.91 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL29783374 | 0.91 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL17127347 | 0.91 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL7400 | 0.91 | EGLN1 (1.00) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL3184813 | 0.88 | EGLN1 (0.93) | EGLN1OR51E2MAPK1SLC13A3LMNA | |
| Alpha-Ketoglutaric Acid SCHEMBL1242830 | 0.88 | EGLN1 (0.93) | EGLN1OR51E2MAPK1SLC13A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008091627-A2 | METHODS AND ORGANISMS FOR GROWTH-COUPLED PRODUCTION OF 3-HYDROXYPROPIONIC ACID | GENOMATICA, INC. (US) | 2008-07-31 | — | — | WO | disclosed |