Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 3/20 | 0.35 |
| ▸ | DNM1L | O00429 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737961 | 0.90 | GAA (0.39) | GAATSHRHTTCXCR2MAPK1 | |
| SCHEMBL4737675 | 0.90 | GAA (0.42) | GAATSHRHTTPDK1CXCR2 | |
| SCHEMBL4738932 | 0.85 | GAA (0.41) | GAATSHRHTTCXCR2MAPK1 | |
| SCHEMBL4738953 | 0.84 | GAA (0.40) | GAATSHRHTTCXCR2MAPK1 | |
| SCHEMBL4735442 | 0.84 | AR (0.43) | GAATSHRHTTPDK1MAPK1 | |
| SCHEMBL4737103 | 0.84 | GAA (0.43) | GAATSHRHTTCXCR2MAPK1 | |
| SCHEMBL4738302 | 0.84 | GAA (0.40) | GAATSHRHTTCXCR2MAPK1 | |
| SCHEMBL3063871 | 0.83 | DNM1L (0.38) | GAATSHRHTTMAPK1DNM1L | |
| SCHEMBL3048456 | 0.81 | DNM1L (0.36) | GAATSHRHTTMAPK1DNM1L | |
| SCHEMBL4787168 | 0.80 | TSHR (0.45) | GAATSHRHTTPDK1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |