Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 16/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 16/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739013 | 1.00 | CYP1A1 (0.50) | CYP1A1CYP1B1DPP4MAOBPTGDR2 | |
| SCHEMBL14146303 | 0.90 | CYP1A1 (0.47) | CYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4740433 | 0.90 | CYP1A1 (0.47) | CYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL14146240 | 0.88 | CYP1A1 (0.47) | CYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL14146267 | 0.81 | CYP1A1 (0.44) | CYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4787159 | 0.79 | TNFRSF1A (0.55) | CYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4737608 | 0.79 | TNFRSF1A (0.55) | CYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4736807 | 0.76 | PTGDR2 (0.43) | PTGDR2 | |
| SCHEMBL4737444 | 0.74 | CYP1A1 (0.58) | CYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4737441 | 0.74 | CYP1A1 (0.58) | CYP1A1CYP1B1DPP4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |