Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 16/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 16/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787159 | 1.00 | TNFRSF1A (0.55) | TNFRSF1ACYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4738538 | 0.88 | PPARG (0.44) | TNFRSF1ACYP1A1CYP1B1MAOB | |
| SCHEMBL4738535 | 0.88 | PPARG (0.44) | TNFRSF1ACYP1A1CYP1B1MAOB | |
| SCHEMBL4736808 | 0.87 | TNFRSF1A (0.46) | TNFRSF1ACYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4736804 | 0.87 | TNFRSF1A (0.46) | TNFRSF1ACYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4737599 | 0.86 | DPP4 (0.48) | TNFRSF1ACYP1B1DPP4MAOBCXCL12 | |
| SCHEMBL4737596 | 0.86 | DPP4 (0.48) | TNFRSF1ACYP1B1DPP4MAOBCXCL12 | |
| SCHEMBL4739052 | 0.85 | TNFRSF1A (0.54) | TNFRSF1ACYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4740485 | 0.85 | TNFRSF1A (0.54) | TNFRSF1ACYP1A1CYP1B1DPP4MAOB | |
| SCHEMBL4737511 | 0.84 | PPARG (0.57) | TNFRSF1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087365-A2 | SUBSTITUTED 1, 3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |