Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23103093 | 0.83 | HPGDS (0.44) | GRM5KDM4EHCAR3HDAC1HDAC6 | |
| SCHEMBL14996248 | 0.80 | KDM4E (0.61) | CA12CA1CA2CA9CA14 | |
| SCHEMBL31280187 | 0.80 | KDM4E (0.61) | CA12CA1CA2CA9CA14 | |
| SCHEMBL17670950 | 0.79 | L3MBTL1 (0.58) | CA12CA1CA2CA9CA14 | |
| SCHEMBL12141948 | 0.78 | HPGD (0.51) | KDM4ENAMPTHCAR3L3MBTL1LMNA | |
| SCHEMBL20804091 | 0.78 | GABRA5 (0.44) | GRM5KDM4ENAMPTHCAR3 | |
| SCHEMBL12017909 | 0.78 | BAZ2B (0.53) | GRM5HCAR3HDAC1HDAC6 | |
| SCHEMBL12985976 | 0.77 | NPC1 (0.54) | KDM4ENAMPTHDAC1HDAC6NPC1 | |
| SCHEMBL13043368 | 0.77 | KDM4E (0.51) | KDM4EAPOBEC3AAPOBEC3GL3MBTL1EPHX2 | |
| SCHEMBL19251863 | 0.77 | CA1 (0.56) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8771646-B2 | Nicotinic acid and picolinic acid derived near-infrared fluorophores | VISEN MEDICAL, INC. (US) | 2014-07-08 | — | — | US | disclosed |
| US-20130272967-A1 | Nicotinic Acid and Picolinic Acid Derived Near-Infrared Fluorophores | VISEN MEDICAL, INC. | 2013-10-17 | — | — | US | disclosed |
| US-8455651-B2 | Nicotinic acid and picolinic acid derived near-infrared fluorophores | VISEN MEDICAL, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| US-8173819-B2 | Nicotinic and picolinic acid derived near-infrared fluorophores | VISEN MEDICAL, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-8173819-B2 | Nicotinic and picolinic acid derived near-infrared fluorophores | VISEN MEDICAL, INC. (US) | 2012-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130272967-A1 | Nicotinic Acid and Picolinic Acid Derived Near-Infrared Fluorophores | NAPRT, NAMPT, HCAR2 | CA12 100/4885CA1 110/4885CA2 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.