Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD5 | P21918 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189339 | 0.80 | AKR1B1 (0.46) | CYP2C9KDM4ELMNACYP2C19 | |
| SCHEMBL2011929 | 0.80 | HTR1A (0.44) | HTR1ADRD2DRD3OPRM1OPRK1 | |
| SCHEMBL6249226 | 0.79 | HTR1A (0.60) | HTR1ADRD2DRD3OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL2012929 | 0.79 | HTR1A (0.43) | HTR1ADRD2DRD3OPRM1OPRK1 | |
| SCHEMBL28141464 | 0.77 | AKR1B1 (0.50) | CYP2C9KDM4ELMNACYP2C19ADRA1A | |
| SCHEMBL9614492 | 0.76 | AKR1B1 (0.43) | CYP2C9KDM4ELMNACYP2C19CYP1A2 | |
| SCHEMBL7298930 | 0.76 | HTR1A (0.59) | HTR1ADRD2DRD3OPRM1OPRK1 | |
| SCHEMBL13618631 | 0.73 | HTR1A (0.43) | HTR1ADRD2DRD3OPRM1OPRK1 | |
| SCHEMBL997090 | 0.73 | AKR1B1 (0.56) | CYP2C9KDM4ELMNACYP2C19HSD17B10 | |
| SCHEMBL7299555 | 0.71 | DRD2 (0.55) | HTR1ADRD2DRD3OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084499-A1 | AN INDUSTRIAL PROCESS FOR THE PREPARATION OF PURE ROPINIROLE | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008084499-A1 | AN INDUSTRIAL PROCESS FOR THE PREPARATION OF PURE ROPINIROLE | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-07-17 | — | — | WO | disclosed |
| WO-2007010557-A2 | PROCESS FOR THE PREPARATION OF HIGHLY PURE ROPINIROLE | IND-SWIFT LABORATORIE LIMTED (IN) | 2007-01-25 | — | — | WO | disclosed |
| WO-2007010557-A2 | PROCESS FOR THE PREPARATION OF HIGHLY PURE ROPINIROLE | IND-SWIFT LABORATORIE LIMTED (IN) | 2007-01-25 | — | — | WO | disclosed |