Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.55 |
| ▸ | DRD3 | P35462 | 4/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298930 | 0.91 | HTR1A (0.59) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL7297679 | 0.82 | DRD2 (0.67) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL552965 | 0.80 | DRD3 (0.71) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL28327056 | 0.79 | DRD3 (0.69) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL7299213 | 0.78 | DRD2 (0.55) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL103958 | 0.77 | MAOB (0.50) | DRD2HTR1A | |
| SCHEMBL5743538 | 0.74 | SIGMAR1 (0.49) | — | |
| SCHEMBL12128296 | 0.73 | DRD3 (0.68) | DRD2DRD3OPRM1OPRD1OPRK1 | |
| SCHEMBL829785 | 0.73 | CD44 (0.44) | HTR1A | |
| SCHEMBL29484088 | 0.73 | CD44 (0.44) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304789-B1 | BENZIMIDAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-03-17 | — | — | EP | disclosed |
| US-4925854-A | Benzimidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0304789-A2 | Benzimidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-01 | — | — | EP | disclosed |