Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PPARD | Q03181 | 10/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741580 | 0.90 | PPARA (0.56) | PPARAALDH1A1PPARDPPARGNPC1 | |
| SCHEMBL4740499 | 0.84 | PPARA (0.55) | PPARAALDH1A1SMN1; SMN2PPARDPPARG | |
| SCHEMBL4740491 | 0.84 | ALDH1A1 (0.60) | PPARAALDH1A1SMN1; SMN2PPARDPPARG | |
| SCHEMBL219071 | 0.83 | HSD17B2 (0.41) | PPARAALDH1A1SMN1; SMN2PPARDPPARG | |
| SCHEMBL4738822 | 0.83 | PPARA (0.55) | PPARAALDH1A1SMN1; SMN2PPARDPPARG | |
| SCHEMBL14146852 | 0.81 | PPARA (0.52) | PPARAALDH1A1PPARDPPARGNPC1 | |
| SCHEMBL4737357 | 0.81 | MAPT (0.43) | PPARAALDH1A1SMN1; SMN2PPARDPPARG | |
| SCHEMBL14146844 | 0.80 | PPARA (0.51) | PPARAALDH1A1PPARDPPARGMAPT | |
| SCHEMBL4740525 | 0.79 | PPARA (0.57) | PPARAALDH1A1PPARDPPARGNPC1 | |
| SCHEMBL4739629 | 0.79 | PPARA (0.51) | PPARAALDH1A1PPARDPPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087367-A2 | SUBSTITUTED (PHENYLTHIAZOLYL)-PHENYL-PROPAN-1-ONE AND (PHENYLOXAZODYL)-PHENYL-PROPAN-1-ONE DERIVATIVES, PREPARATIONS AND USES OF SAME | GENFIT (FR) | 2008-07-24 | — | — | WO | disclosed |